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How long does it take for Lotrel to leave system? Over 950 patients received Lotrel once daily in six double-blind, placebo-controlled studies. Lotrel lowered blood pressure within 1 hour, with peak reductions achieved 2-8 hours after dosing. The antihypertensive effect of a single dose persisted for 24 hours.
Is labetalol a selective beta blocker? Labetalol is highly selective for postsynaptic alpha1- adrenergic, and non- selective for beta -adrenergic receptors. It is about equipotent in blocking both beta1- and beta2- receptors. Thus, the labetalol can be thought to be a beta - blocker with some alpha-blocking effects.
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